Product nameAnti-CEACAM7 antibody [BAC2]
See all CEACAM7 primary antibodies
DescriptionMouse monoclonal [BAC2] to CEACAM7
Specificityab26281 recognizes exclusively CEACAM7 transiently expressed on the cell surface of transfected BOSC23 cells. It can be used to distinguish CEACAM7 from all other CEACAM and probably all pregnancy-specific glycoprotein molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable and transiently transfected mammalian cells expressing individual CEA family members.
Tested applicationsSuitable for: IHC-P, Flow Cyt, ELISA, IHC-Frmore details
Species reactivityReacts with: Human
ab26281 was generated by immunisation of BALB/c mice with a CEACAM7/Fc fusion protein.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.01% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab26281 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|Flow Cyt||Use at an assay dependent concentration.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|ELISA||Use at an assay dependent concentration.|
|IHC-Fr||Use at an assay dependent concentration.|
Tissue specificityStrongly down-regulated in colonic adenocarcinomas.
Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localizationCell membrane.
- Information by UniProt
- Carcinoembryonic antigen CGM 2 antibody
- Carcinoembryonic antigen CGM2 antibody
- Carcinoembryonic antigen gene family member 2 antibody
Immunohistochemical analysis of gastric carcinoma tissue, stainin CEACAM7 with ab26281.
Antigen retrieval was performed by heat mediation in a citrate buffer (pH 6). Sections were blocked with 10% normal goat serum in PBS for 30 minutes followed by incubation overnight at 4°C with the primary antibody (1/100 in 1% BSA). Staining was detected using DAB.
This product has been referenced in:
- Kobayashi M et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). Read more (PubMed: 23099808) »
- Zhou J et al. Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 9:172 (2011). IHC-P ; Human . Read more (PubMed: 22195770) »