Anti-CEACAM7 antibody [BAC2] (ab26281)
Key features and details
- Mouse monoclonal [BAC2] to CEACAM7
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-CEACAM7 antibody [BAC2]
See all CEACAM7 primary antibodies -
Description
Mouse monoclonal [BAC2] to CEACAM7 -
Host species
Mouse -
Specificity
ab26281 recognizes exclusively CEACAM7 transiently expressed on the cell surface of transfected BOSC23 cells. It can be used to distinguish CEACAM7 from all other CEACAM and probably all pregnancy-specific glycoprotein molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable and transiently transfected mammalian cells expressing individual CEA family members. -
Species reactivity
Reacts with: Human -
Immunogen
ab26281 was generated by immunisation of BALB/c mice with a CEACAM7/Fc fusion protein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
BAC2 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Target
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Tissue specificity
Strongly down-regulated in colonic adenocarcinomas. -
Sequence similarities
Belongs to the immunoglobulin superfamily. CEA family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1087 Human
- SwissProt: Q14002 Human
- Unigene: 74466 Human
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Alternative names
- Carcinoembryonic antigen CGM 2 antibody
- Carcinoembryonic antigen CGM2 antibody
- Carcinoembryonic antigen gene family member 2 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab26281 has been referenced in 3 publications.
- Kobayashi M et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). PubMed: 23099808
- Zhou J et al. Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 9:172 (2011). IHC-P ; Human . PubMed: 22195770
- Thomas SN et al. Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow. J Biol Chem 283:15647-55 (2008). Flow Cyt ; Human . PubMed: 18375392