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    ceacam7-antibody-bac2-ab26281.pdf

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Tags & Cell Markers Cell Type Markers Tumor Associated
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Anti-CEACAM7 antibody [BAC2] (ab26281)

  • Datasheet
  • SDS
Reviews (1) Submit a question References (3)

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Key features and details

  • Mouse monoclonal [BAC2] to CEACAM7
  • Reacts with: Human
  • Isotype: IgG1

You may also be interested in

Protein
Product image
Recombinant Human CEACAM7 protein (ab156717)
Secondary
Product image
Goat Anti-Mouse IgG H&L (HRP) (ab205719)

View more associated products

Overview

  • Product name

    Anti-CEACAM7 antibody [BAC2]
    See all CEACAM7 primary antibodies
  • Description

    Mouse monoclonal [BAC2] to CEACAM7
  • Host species

    Mouse
  • Specificity

    ab26281 recognizes exclusively CEACAM7 transiently expressed on the cell surface of transfected BOSC23 cells. It can be used to distinguish CEACAM7 from all other CEACAM and probably all pregnancy-specific glycoprotein molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable and transiently transfected mammalian cells expressing individual CEA family members.
  • Species reactivity

    Reacts with: Human
  • Immunogen

    ab26281 was generated by immunisation of BALB/c mice with a CEACAM7/Fc fusion protein.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    BAC2
  • Isotype

    IgG1
  • Research areas

    • Tags & Cell Markers
    • Cell Type Markers
    • Tumor Associated

Associated products

  • Compatible Secondaries

    • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
    • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
  • Isotype control

    • Mouse IgG1, kappa monoclonal [15-6E10A7] - Isotype Control (ab170190)
  • Recombinant Protein

    • Recombinant Human CEACAM7 protein (ab156717)

Target

  • Tissue specificity

    Strongly down-regulated in colonic adenocarcinomas.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession Q14002 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1087 Human
    • SwissProt: Q14002 Human
    • Unigene: 74466 Human
    • Alternative names

      • Carcinoembryonic antigen CGM 2 antibody
      • Carcinoembryonic antigen CGM2 antibody
      • Carcinoembryonic antigen gene family member 2 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 7 antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 7 antibody
      • CEA antibody
      • CEACAM 7 antibody
      • CEACAM7 antibody
      • CEAM7_HUMAN antibody
      • CGM 2 antibody
      • CGM2 antibody
      see all

    Protocols

    • Flow cytometry protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (3)

    Publishing research using ab26281? Please let us know so that we can cite the reference in this datasheet.

    ab26281 has been referenced in 3 publications.

    • Kobayashi M  et al. Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma. Br J Cancer 107:1745-53 (2012). PubMed: 23099808
    • Zhou J  et al. Dynamic expression of CEACAM7 in precursor lesions of gastric carcinoma and its prognostic value in combination with CEA. World J Surg Oncol 9:172 (2011). IHC-P ; Human . PubMed: 22195770
    • Thomas SN  et al. Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow. J Biol Chem 283:15647-55 (2008). Flow Cyt ; Human . PubMed: 18375392

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-CEACAM7 antibody [BAC2]

    Good
    Abreviews
    Abreviews
    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample
    Human Tissue sections (normal tissue array - liver/lung/breast/kidney/col)
    Specification
    normal tissue array - liver/lung/breast/kidney/col
    Fixative
    Paraformaldehyde
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: citrate
    Permeabilization
    No
    Blocking step
    Peroxidase block as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 100%
    Read More

    Abcam user community

    Verified customer

    Submitted Mar 27 2009

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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