Anti-GULP antibody (ab97669)
Key features and details
- Rabbit polyclonal to GULP
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-GULP antibody
See all GULP primary antibodies -
Description
Rabbit polyclonal to GULP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide corresponding to Human GULP aa 241-304.
Database link: NP_057399 -
Positive control
- 293T, HeLa, HepG2, MOLT4 or NIH3T3 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97669 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 35 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 35 kDa. |
Target
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Function
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6. -
Tissue specificity
Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary. -
Sequence similarities
Belongs to the ced-6 family.
Contains 1 PID domain. -
Cellular localization
Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes. - Information by UniProt
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Database links
- Entrez Gene: 51454 Human
- Entrez Gene: 70676 Mouse
- Entrez Gene: 314543 Rat
- Omim: 608165 Human
- SwissProt: Q9UBP9 Human
- SwissProt: Q8K2A1 Mouse
- SwissProt: Q5PQS4 Rat
- Unigene: 470887 Human
see all -
Alternative names
- CED6 antibody
- Cell death protein 6 homolog antibody
- Engulfment adapter protein antibody
see all
Images
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All lanes : Anti-GULP antibody (ab97669) at 1/1000 dilution
Lane 1 : HepG2 whole cell lysate
Lane 2 : MOLT4 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 35 kDa
10% SDS-PAGE. -
Anti-GULP antibody (ab97669) at 1/1000 dilution + NIH3T3 whole cell lysate at 30 µg
Predicted band size: 35 kDa
10% SDS-PAGE.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab97669 has been referenced in 1 publication.
- Sullivan CS et al. The adaptor protein GULP promotes Jedi-1-mediated phagocytosis through a clathrin-dependent mechanism. Mol Biol Cell 25:1925-36 (2014). PubMed: 24743597