Cefoperazone, beta-lactamase inhibitor. Antibiotic agent. (ab143256)

Overview

  • Product name

    Cefoperazone, beta-lactamase inhibitor. Antibiotic agent.
  • Description

    Potent β-lactamase inhibitor. Antibiotic agent.
  • Biological description

    Potent β-lactamase inhibitor. Antibiotic agent. Inhibits peptidoglycan synthesis. Active against Pseudomonas. Shows broad spectrum bactericidal effects in vivo.
  • Purity

    > 99%
  • CAS Number

    62893-19-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (6R,7R)-7-[[(2R)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Molecular weight

    645.67
  • Molecular formula

    C25H27N9O8S2
  • PubChem identifier

    44187
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1(CS[C@]2(N(C=1C(=O)O)C([C@H]2NC(=O)[C@@H](C3=CC=C(C=C3)O)NC(N4C(C(N(CC4)CC)=O)=O)=O)=O)[H])CSC5=NN=NN5C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Wang S  et al. [An experimental study of antibiotic -- induced endotoxin release in Pseudomonas aeruginosa bacteremia inburned rats]. Zhonghua Shao Shang Za Zhi 16:93-5 (2000). Read more (PubMed: 11876851) »
  • Araki A & Sendo F Reduced anti-Pseudomonas aeruginosa activity of a cephalosporin, cefodizime, in rats whose neutrophils were selectively depleted by a monoclonal antibody. Microbiol Immunol 40:333-8 (1996). Read more (PubMed: 8999285) »
  • Lou S  et al. Influence of cefoperazone and azithromycin on the pharmacokinetics of pazufloxacin in rats. Eur J Drug Metab Pharmacokinet 32:219-23 (0). Read more (PubMed: 18348471) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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