Overview

  • Product name

    Anti-CELSR2 antibody - N-terminal
    See all CELSR2 primary antibodies
  • Description

    Rabbit polyclonal to CELSR2 - N-terminal
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human CELSR2 (N terminal). 20 amino acid peptide from N-terminal extracellular domain; NP_001399.1.
    Database link: Q9HCU4

  • Positive control

    • Human breast, lobular epithelium.

Properties

Applications

Our Abpromise guarantee covers the use of ab189009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 16 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor that may have an important role in cell/cell signaling during nervous system formation.
  • Tissue specificity

    Highest expression in brain and testis.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 9 cadherin domains.
    Contains 7 EGF-like domains.
    Contains 1 GPS domain.
    Contains 1 laminin EGF-like domain.
    Contains 2 laminin G-like domains.
  • Post-translational
    modifications

    The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog antibody
    • Cadherin EGF LAG seven-pass G-type receptor 2 antibody
    • Cadherin family member 10 antibody
    • CDHF10 antibody
    • CELR2_HUMAN antibody
    • Celsr2 antibody
    • EGF like domain multiple 2 antibody
    • EGF-like protein 2 antibody
    • EGFL2 antibody
    • epidermal growth factor like 2 antibody
    • Epidermal growth factor-like protein 2 antibody
    • Flamingo homolog 3 antibody
    • Flamingo1 antibody
    • KIAA0279 antibody
    • MEGF3 antibody
    • Multiple EGF-like domains protein 3 antibody
    • Multiple epidermal growth factor-like domains 3 antibody
    • Multiple epidermal growth factor-like domains protein 3 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast, lobular epithelium labeling CELSR2 with ab189009 at 16 µg/ml.

References

ab189009 has not yet been referenced specifically in any publications.

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