Anti-CENPH antibody (ab230202)

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Overview

  • Product name

    Anti-CENPH antibody
    See all CENPH primary antibodies

  • Description

    Rabbit polyclonal to CENPH

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant full length protein corresponding to Human CENPH aa 1-247.
    Sequence:

    MEEQPQMQDADEPADSGGEGRAGGPPQVAGAQAACSEDRMTLLLRLRAQT KQQLLEYKSMVDASEEKTPEQIMQEKQIEAKIEDLENEIEEVKVAFEIKK LALDRMRLSTALKKNLEKISRQSSVLMDNMKHLLELNKLIMKSQQESWDL EEKLLDIRKKRLQLKQASESKLLEIQTEKNKQKIDLDSMENSERIKIIRQ NLQMEIKITTVIQHVFQNLILGSKVNWAEDPALKEIVLQLEKNVDMM


    Database link: Q9H3R5

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • IHC-P: Human tonsil tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.

  • Sequence similarities

    Belongs to the centromere protein H family.

  • Cellular localization

    Nucleus. Chromosome > centromere > kinetochore. Associates with active centromere-kinetochore complexes throughout the cell cycle. Colocalizes with inner kinetochore plate proteins CENPA and CENPC1 during both interphase and metaphase.
  • Information by UniProt

  • Database links

    • Alternative names

      • CENP H antibody
      • CENP-H antibody
      • CENPH antibody
      • CENPH_HUMAN antibody
      • Centromere protein H antibody
      • ICEN35 antibody
      • Interphase centromere complex protein 35 antibody
      • Kinetochore protein CENP H antibody
      • NNF1 antibody
      • NNF1, MIND kinetochore complex component, homolog antibody
      • PMF1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CENPH antibody (ab230202)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CENPH antibody (ab230202)

      Paraffin-embedded human tonsil tissue stained for CENPH using ab230202 at 1/100 dilution in immunohistochemical analysis.

    References

    ab230202 has not yet been referenced specifically in any publications.

    Publishing research using ab230202? Please let us know so that we can cite the reference in this datasheet.

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