Key features and details
- Rabbit polyclonal to Centaurin alpha 1 - N-terminal
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Centaurin alpha 1 antibody - N-terminal
See all Centaurin alpha 1 primary antibodies
DescriptionRabbit polyclonal to Centaurin alpha 1 - N-terminal
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Recombinant fragment corresponding to Human Centaurin alpha 1 (N terminal).
Database link: O75689
- Mouse brain lysate; Human colon cancer tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197380 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/200.|
|WB||1/200 - 1/1000. Predicted molecular weight: 43 kDa.|
RelevanceThe centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.
Cellular localizationCytoplasmic, Nuclear and Plasma membrane
- ArfGAP with dual PH domains 1 antibody
- CENTA 1 antibody
- CENTA1 antibody
Anti-Centaurin alpha 1 antibody - N-terminal (ab197380) at 1/500 dilution + mouse brain lysate at 40 µg
Anti-rabbit IgG at 1/8000 dilution
Predicted band size: 43 kDa
Exposure time: 15 seconds
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue, labeling Centaurin alpha 1 with ab197380 at a 1/100 dilution.
ab197380 has been referenced in 1 publication.
- Van Duzer A et al. ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival. Life Sci Alliance 2:N/A (2019). PubMed: 31792062