Anti-CEP152 antibody (ab110825)

Reviews (1)Q&A (1)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CEP152 antibody (ab110825)

    Key features and details

    • Rabbit polyclonal to CEP152
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-CEP152 antibody
      See all CEP152 primary antibodies

    • Description

      Rabbit polyclonal to CEP152

    • Host species

      Rabbit

    • Tested applications

      Suitable for: IHC-Pmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse

    • Immunogen

      Synthetic peptide derived from an internal sequence of Human CEP152.

    • Positive control

      • Human lymph node tissue.

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab110825 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Involvement in disease

      Defects in CEP152 are the cause of microcephaly primary type 4 (MCPH4) [MIM:604321]. A disease defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Affected individuals are mentally retarded. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits due to degenerative brain disorder.

    • Cellular localization

      Cytoplasm > cytoskeleton > centrosome.
    • Information by UniProt

    • Database links

      • Alternative names

        • Asterless antibody
        • CE152_HUMAN antibody
        • Centrosomal protein 152kDa antibody
        • Centrosomal protein of 152 kDa antibody
        • Cep152 antibody
        • FLJ21594 antibody
        • KIAA0912 antibody
        • MCPH4 antibody
        • MCPH9 antibody
        • Microcephaly primary autosomal recessive 4 antibody
        • SCKL5 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CEP152 antibody (ab110825)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CEP152 antibody (ab110825)
        ab110825, at 1/50 dilution, staining CEP152 in paraffin-embedded Human lymph node tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of immunising peptide.

      References (0)

      Publishing research using ab110825? Please let us know so that we can cite the reference in this datasheet.

      ab110825 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

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      1-2 of 2 Abreviews or Q&A

      Immunocytochemistry/ Immunofluorescence abreview for Anti-CEP152 antibody

       Inconclusive
      Abreviews
      abreview image
      Application
      Immunocytochemistry/ Immunofluorescence
      Sample
      Mouse Cell (pre-B cell line)
      Permeabilization
      Yes - 0.1% Triton X-100
      Specification
      pre-B cell line
      Blocking step
      Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
      Fixative
      Paraformaldehyde
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      Abcam user community

      Verified customer

      Submitted Jun 16 2016

      Question

      That sounds great. We would like to proceed and buy ab110825 and test it in mouse cells. We will wait for the discount code before ordering. Thanks,

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      Answer

      Thank you for your message. I am very pleased to hear you would like to accept our offer and test ab110825 in mouse. DISCOUNT CODE: 100%ABR-T7TMA Expiration date: 16th Jan 2012 This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for mouse and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code. Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount. We look forward to receiving your Abreview and wish you luck with your research.

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