Anti-CEP57 antibody (ab104010)
Key features and details
- Rabbit polyclonal to CEP57
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CEP57 antibody
See all CEP57 primary antibodies -
Description
Rabbit polyclonal to CEP57 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 86-251 of Human CEP57 (AAH01233).
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Positive control
- NT2D1 whole cell lysate; NCI-N87 xenograft; MCF-7 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab104010 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 57 kDa.
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IHC-P |
1/100 - 1/500. Heat mediated antigen retrieval using 10mM Citrate buffer or Tris-EDTA buffer (pH8.0) is recommended.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
IHC-P
1/100 - 1/500. Heat mediated antigen retrieval using 10mM Citrate buffer or Tris-EDTA buffer (pH8.0) is recommended. |
Target
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Function
Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the translokin family. -
Domain
The C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro.
The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization. -
Cellular localization
Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. - Information by UniProt
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Database links
- Entrez Gene: 353245 Cow
- Entrez Gene: 9702 Human
- Entrez Gene: 74360 Mouse
- Entrez Gene: 315423 Rat
- Omim: 607951 Human
- SwissProt: Q865V0 Cow
- SwissProt: Q86XR8 Human
- SwissProt: Q8CEE0 Mouse
see all -
Alternative names
- Centrosomal protein 57kDa antibody
- Centrosomal protein of 57 kDa antibody
- Cep57 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab104010 has not yet been referenced specifically in any publications.