Overview

  • Product name

  • Description

    Mouse polyclonal to CEP57
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Chimpanzee, Rhesus monkey
  • Immunogen

    Full length protein, corresponding to amino acids 1-500 of Human CEP57 (NP_055494.2).

  • Positive control

    • CEP57 transfected 293T cell lysate; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab169301 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function

    Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the translokin family.
  • Domain

    The C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro.
    The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization.
  • Cellular localization

    Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > centrosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • Centrosomal protein 57kDa antibody
    • Centrosomal protein of 57 kDa antibody
    • Cep57 antibody
    • Cep57 protein antibody
    • CEP57_HUMAN antibody
    • FGF2 interacting protein antibody
    • FGF2-interacting protein antibody
    • KIAA0092 antibody
    • MVA2 antibody
    • PIG8 antibody
    • Proliferation inducing protein 8 antibody
    • Testis specific protein 57 antibody
    • Testis-specific protein 57 antibody
    • Translokin antibody
    • TSP57 antibody
    see all

Images

  • All lanes : Anti-CEP57 antibody (ab169301) at 1 µg/ml

    Lane 1 : CEP57-transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Developed using the ECL technique.

    Predicted band size: 57 kDa

  • Immunofluorescent analysis of HeLa cells labeling CEP57 with ab169301 at 10 µg/ml.

References

This product has been referenced in:

See 1 Publication for this product

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