Anti-Ceramide synthase 1/LAG1 antibody (ab198799)
Key features and details
- Rabbit polyclonal to Ceramide synthase 1/LAG1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Ceramide synthase 1/LAG1 antibody
See all Ceramide synthase 1/LAG1 primary antibodies -
Description
Rabbit polyclonal to Ceramide synthase 1/LAG1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human Ceramide synthase 1/LAG1. (Near the C terminal; NP_067090).
Database link: P27544 -
Positive control
- Human ovarian cancer and prostate cancer tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab198799 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200.
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Notes |
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IHC-P
1/50 - 1/200. |
Target
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Function
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. -
Sequence similarities
Contains 1 TLC (TRAM/LAG1/CLN8) domain. -
Cellular localization
Endoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. Isoform 1 may recycle from the Golgi to the endoplasmic reticulum. - Information by UniProt
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Database links
- Entrez Gene: 10715 Human
- Entrez Gene: 93898 Mouse
- Omim: 606919 Human
- SwissProt: P27544 Human
- SwissProt: P27545 Mouse
- Unigene: 412355 Human
- Unigene: 258280 Mouse
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Alternative names
- Ceramide synthase 1 antibody
- CerS1 antibody
- CERS1_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab198799 has not yet been referenced specifically in any publications.