Product nameAnti-Ceramide synthase 1/LAG1 antibody [EPR5816(2)]
See all Ceramide synthase 1/LAG1 primary antibodies
DescriptionRabbit monoclonal [EPR5816(2)] to Ceramide synthase 1/LAG1
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC,IHC-P or IP
Species reactivityReacts with: Human
Synthetic peptide within Human Ceramide synthase 1/LAG1 aa 1-100. The exact sequence is proprietary.
- Human fetal brain lysate
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as Ceramide synthase 1
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (KD)KD = 7.40 x 10 -11 M Learn more about KD
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Our Abpromise guarantee covers the use of ab131169 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 40 kDa.|
FunctionMay be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.
Sequence similaritiesContains 1 TLC (TRAM/LAG1/CLN8) domain.
Cellular localizationEndoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. Isoform 1 may recycle from the Golgi to the endoplasmic reticulum.
- Information by UniProt
- Ceramide synthase 1 antibody
- CerS1 antibody
- CERS1_HUMAN antibody
Anti-Ceramide synthase 1/LAG1 antibody [EPR5816(2)] (ab131169) at 1/1000 dilution + Human fetal brain lysate at 10 µg
Goat Anti-rabbit HRP at 1/2000 dilution
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
ab131169 has not yet been referenced specifically in any publications.