Overview

  • Product name

  • Description

    Rabbit polyclonal to CerS2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human CerS2 (internal sequence). The exact sequence is proprietary.
    Database link: Q96G23

  • Positive control

    • ICC/IF: HeLa cells. WB: HEK-293T and HeLa whole cell extracts.
  • General notes

     This product was previously labelled as Ceramide synthase 2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab227501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
  • Tissue specificity

    Expressed in kidney, liver, brain, heart, placenta and lung.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
    Contains 1 TLC (TRAM/LAG1/CLN8) domain.
  • Cellular localization

    Nucleus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Ceramide synthase 2 antibody
    • CerS 2 antibody
    • CerS2 antibody
    • CERS2_HUMAN antibody
    • FLJ10243 antibody
    • L3 antibody
    • LAG1 homolog ceramide synthase 2 antibody
    • LAG1 longevity assurance 2 antibody
    • LAG1 longevity assurance homolog 2 antibody
    • LASS 2 antibody
    • Longevity assurance (LAG1 S. cerevisiae) homolog 2 antibody
    • MGC987 antibody
    • SP 260 antibody
    • SP260 antibody
    • TMSG 1 antibody
    • TMSG1 antibody
    • Tumor metastasis suppressor antibody
    • Tumor metastasis suppressor gene 1 protein antibody
    • Tumor metastasis-suppressor gene 1 protein antibody
    see all

Images

  • 4% paraformaldehyde-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for CerS2 (green) using ab227501 at 1/500 dilution in ICC/IF.

    Blue: Hoechst 33342 staining.

  • All lanes : Anti-CerS2 antibody (ab227501) at 1/1000 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract
    Lane 2 : HeLa (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 45 kDa



    10% SDS-PAGE gel.

References

ab227501 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227501.
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