Overview

  • Product name

    Cerulenin, Fatty acid synthase inhibitor
  • Description

    Antifungal antibiotic. Fatty acid synthase inhibitor
  • Biological description

    Antifungal antibiotic. Fatty Acid Synthase (FAS) and steriod biosynthesis inhibitor. Binds covalently to the active center cysteine of the FAS condensing enzyme domain. Induces apoptosis in vivo.
  • Purity

    > 98%
  • CAS Number

    17397-89-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Murata S  et al. Fatty acid synthase inhibitor cerulenin suppresses liver metastasis of colon cancer in mice. Cancer Sci 101:1861-5 (2010). Read more (PubMed: 20491775) »
  • Inokoshi J  et al. Cerulenin-resistant mutants of Saccharomyces cerevisiae with an altered fatty acid synthase gene. Mol Gen Genet 244:90-6 (1994). Read more (PubMed: 8041367) »
  • Funabashi H  et al. Binding site of cerulenin in fatty acid synthetase. J Biochem 105:751-5 (1989). Read more (PubMed: 2666407) »

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