• Product name

    Anti-Ceruloplasmin antibody
    See all Ceruloplasmin primary antibodies
  • Description

    Goat polyclonal to Ceruloplasmin
  • Host species

  • Specificity

    By immunoelectrophoresis and ELISA this antibody reacts specifically with ceruloplasmin. No antibody was detected against other serum proteins.
  • Tested applications

    Suitable for: WB, ELISA, ICCmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Unfortunately, this information is considered to be commercially sensitive


  • Form

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab19171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 122 kDa.
ELISA 1/100 - 1/1000.
ICC 1/200 - 1/2000.


  • Function

    Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane.
  • Tissue specificity

    Expressed by the liver and secreted in plasma.
  • Involvement in disease

    Defects in CP are the cause of aceruloplasminemia (ACERULOP) [MIM:604290]. It is an autosomal recessive disorder of iron metabolism characterized by iron accumulation in the brain as well as visceral organs. Clinical features consist of the triad of retinal degeneration, diabetes mellitus and neurological disturbances.
    Note=Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
  • Sequence similarities

    Belongs to the multicopper oxidase family.
    Contains 3 F5/8 type A domains.
    Contains 6 plastocyanin-like domains.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • CERU_HUMAN antibody
    • Ceruloplasmin antibody
    • CP 2 antibody
    • CP antibody
    • CP2 antibody
    • Ferroxidase antibody
    see all


This product has been referenced in:

  • Zanardi A  et al. Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia. EMBO Mol Med 10:91-106 (2018). Read more (PubMed: 29183916) »
  • Wisniewska M  et al. Copper to Zinc Ratio as Disease Biomarker in Neonates with Early-Onset Congenital Infections. Nutrients 9:N/A (2017). WB ; Human . Read more (PubMed: 28358335) »
See all 6 Publications for this product

Customer reviews and Q&As

1-2 of 2 Q&A


Thank you for your patience. I am afraid that the originator of the product can only confirm that the antibody was made with the whole protein and not a synthesized peptide, and that the goat was immunized with native protein ceruloplasmin. I am sorry but this is all the information we have on this product. If you require any other information, please do not hesitate to contact me.

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Thank you for your enquiry. Ab8749 is a polyclonal antibody raised to the full length protein, and will therefore consist of a mixed population of IgGs, each of which will recognise a different epitope. The immunogen for Ab19171 is considered commercially sensitive, so I do not have any further information on the epitope of this antibody. I hope this information helps. Please do not hesitate to contact us if you need anything further.

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