Anti-CES2 antibody (ab126970)

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Overview

  • Product name

    Anti-CES2 antibody
    See all CES2 primary antibodies

  • Description

    Rabbit polyclonal to CES2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment corresponding to Human CES2 aa 374-546.
    Database link: O00748

  • Positive control

    • HepG2 whole cell lysate (ab7900); Human Colon carcinoma tissue.

  • General notes

    Keep as concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab126970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 62 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.

  • Tissue specificity

    Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.

  • Sequence similarities

    Belongs to the type-B carboxylesterase/lipase family.

  • Post-translational
    modifications

    Glycosylated.

  • Cellular localization

    Endoplasmic reticulum lumen.
  • Information by UniProt

  • Database links

    • Alternative names

      • Carboxylesterase 2 (intestine, liver) antibody
      • Carboxylesterase 2 antibody
      • CE-2 antibody
      • CES2 antibody
      • CES2A1 antibody
      • Cocaine esterase antibody
      • EC 3.1.1.1 antibody
      • EST2_HUMAN antibody
      • hCE-2 antibody
      • ICE antibody
      • Iintestinal carboxylesterase liver carboxylesterase 2 antibody
      • Intestinal carboxylesterase; liver carboxylesterase-2 antibody
      • Methylumbelliferyl acetate deacetylase 2 antibody
      • PCE 2 antibody
      • PCE-2 antibody
      see all

    Images

    • Western blot - Anti-CES2 antibody (ab126970)
      Western blot - Anti-CES2 antibody (ab126970)
      Anti-CES2 antibody (ab126970) at 1/2000 dilution + HepG2 whole cell lysate at 30 µg

      Predicted band size: 62 kDa



      7.5% SDS PAGE
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CES2 antibody (ab126970)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CES2 antibody (ab126970)
      ab126970, at 1/500 dilution, staining CES2 in paraffin-embedded Human Colon carcinoma tissue by Immunohistochemistry.

    References

    ab126970 has not yet been referenced specifically in any publications.

    Publishing research using ab126970? Please let us know so that we can cite the reference in this datasheet.

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