Anti-CES3/TGH antibody (ab215045)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-CES3/TGH antibody
See all CES3/TGH primary antibodies -
Description
Sheep polyclonal to CES3/TGH -
Host species
Sheep -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat
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Immunogen
Recombinant fragment corresponding to Mouse CES3/TGH aa 19-561. NS0-derived
Sequence:YPSSPPVVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPP QPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLY LNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTI QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIF GESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVA TLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFL PTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPLAE GKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLFQDL MADVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGDHGD EIFSVFGSPFLKDGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPEY DQKEGYLKIGASTQAAQRLKDKEVSFWAELRAKESAQRPSHRE
Database link: Q8VCT4 -
Positive control
- Mouse lung tissue lysate.
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General notes
This product was previously labelled as CES3
Properties
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Form
Lyophilised:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 100% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
The IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab215045 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/2000. Predicted molecular weight: 62 kDa. |
Target
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Function
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. -
Tissue specificity
Expressed in liver, colon and small intestine. -
Sequence similarities
Belongs to the type-B carboxylesterase/lipase family. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Endoplasmic reticulum lumen. - Information by UniProt
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Database links
- Entrez Gene: 104158 Mouse
- Entrez Gene: 113902 Rat
- SwissProt: Q8VCT4 Mouse
- SwissProt: P16303 Rat
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Alternative names
- Carboxylesterase 3 antibody
- CES 3 antibody
- Ces3 antibody
see all
Images
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Western blot - Anti-CES3/TGH antibody (ab215045)Anti-CES3/TGH antibody (ab215045) at 1/1000 dilution + mouse lung tissue lysate
Predicted band size: 62 kDa
Protocols
Datasheets and documents
References
ab215045 has not yet been referenced specifically in any publications.
