Anti-CETP antibody (ab137396)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-CETP antibody
See all CETP primary antibodies -
Description
Rabbit polyclonal to CETP -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 64-386 of Human CETP (Uniprot ID P11597).
-
Positive control
- Molt-4, HeLa, HepG2 whole cell lysate (ab7900), DLD1 xenograft tissue
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab137396 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 55 kDa. | |
| IHC-P | 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Involvement in disease
Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels. -
Sequence similarities
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. -
Cellular localization
Secreted > extracellular space. - Information by UniProt
-
Database links
- Entrez Gene: 1071 Human
- Omim: 118470 Human
- SwissProt: P11597 Human
- Unigene: 89538 Human
-
Alternative names
- BPIFF antibody
- CETP antibody
- CETP_HUMAN antibody
see all
Images
-
Western blot - Anti-CETP antibody (ab137396)Anti-CETP antibody (ab137396) at 1/1000 dilution + Hep G2 whole cell lysate at 30 µg
Predicted band size: 55 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CETP antibody (ab137396)Immunohistochemical analysis of paraffin embedded DLD1 xenograft tissue labelled with ab137396 at 1/500 dilution.
References
ab137396 has not yet been referenced specifically in any publications.
