CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
![Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)](https://www.abcam.com/ps/products/119/ab119483/Images/ab119483-132798-anti-cd42a-gp-ix-antibody-gr-p-cf405m-flow-cytometry.jpg "Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)")
Key features and details
- CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: CF405M. Ex: 408nm, Em: 452nm
- Isotype: IgG2a
Overview
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Product name
CF405M Anti-CD42a/GP-IX antibody [GR-P]
See all CD42a/GP-IX primary antibodies -
Description
CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX -
Host species
Mouse -
Conjugation
CF405M. Ex: 408nm, Em: 452nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to CD42a/GP-IX.
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Positive control
- Human platelets in normal peripheral blood.
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General notes
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
Previously labelled as CD42a.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Buffer containing antibody stabilizer solution. -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Monoclonal -
Clone number
GR-P -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab119483 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 5µl for 106 cells.
ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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| Notes |
|---|
|
Flow Cyt
Use 5µl for 106 cells. ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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Target
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Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
Involvement in disease
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
Sequence similarities
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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Alternative names
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
Images
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Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
ab119483, at 5 µl/106 cells, staining CD42a/GP-IX in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.
Datasheets and documents
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Datasheet download
References (0)
ab119483 has not yet been referenced specifically in any publications.
