CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
Key features and details
- CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: CF405M. Ex: 408nm, Em: 452nm
- Isotype: IgG2a
Overview
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Product name
CF405M Anti-CD42a/GP-IX antibody [GR-P]
See all CD42a/GP-IX primary antibodies -
Description
CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX -
Host species
Mouse -
Conjugation
CF405M. Ex: 408nm, Em: 452nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to CD42a/GP-IX.
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Positive control
- Human platelets in normal peripheral blood.
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General notes
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
Previously labelled as CD42a.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Buffer containing antibody stabilizer solution. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Monoclonal -
Clone number
GR-P -
Isotype
IgG2a -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab119483 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt | Use 5µl for 106 cells. ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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Target
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Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
Involvement in disease
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
Sequence similarities
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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Alternative names
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
Images
Datasheets and documents
References (0)
ab119483 has not yet been referenced specifically in any publications.