CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)

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Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)

    Key features and details

    • CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: CF405M. Ex: 408nm, Em: 452nm
    • Isotype: IgG2a

    Overview

    • Product name

      CF405M Anti-CD42a/GP-IX antibody [GR-P]
      See all CD42a/GP-IX primary antibodies

    • Description

      CF405M Mouse monoclonal [GR-P] to CD42a/GP-IX

    • Host species

      Mouse

    • Conjugation

      CF405M. Ex: 408nm, Em: 452nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Tissue, cells or virus corresponding to CD42a/GP-IX.

    • Positive control

      • Human platelets in normal peripheral blood.

    • General notes

      CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

      Previously labelled as CD42a. 

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C.

    • Storage buffer

      pH: 7.20
      Preservative: 0.09% Sodium azide

      Buffer containing antibody stabilizer solution.
    • Concentration information loading...

    • Purity

      Immunogen affinity purified

    • Clonality

      Monoclonal

    • Clone number

      GR-P

    • Isotype

      IgG2a

    • Research areas

    Applications

    Our Abpromise guarantee covers the use of ab119483 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 5µl for 106 cells.

    ab126036 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.

    • Involvement in disease

      Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.

    • Sequence similarities

      Contains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CD42a antibody
        • Glycoprotein 9 antibody
        • Glycoprotein IX antibody
        • Glycoprotein IX (platelet) antibody
        • Glycoprotein IX precursor antibody
        • GP IX antibody
        • GP-IX antibody
        • GP9 antibody
        • GPIX antibody
        • GPIX_HUMAN antibody
        • Platelet glycoprotein IX antibody
        see all

      Images

      • Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
        Flow Cytometry - CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)

        ab119483, at 5 µl/106 cells, staining CD42a/GP-IX in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.

      References (0)

      Publishing research using ab119483? Please let us know so that we can cite the reference in this datasheet.

      ab119483 has not yet been referenced specifically in any publications.

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