CF405M Anti-Integrin alpha 2 antibody [TEA1/41] (ab115797)
![Flow Cytometry - CF405M Anti-Integrin alpha 2 antibody [TEA1/41] (ab115797)](https://www.abcam.com/ps/products/115/ab115797/Images/ab115797-127938-anti-integrin-alpha-2-antibody-tea1-41-cf405m-flow-cytometry.jpg "Flow Cytometry - CF405M Anti-Integrin alpha 2 antibody [TEA1/41] (ab115797)")
Key features and details
- CF405M Mouse monoclonal [TEA1/41] to Integrin alpha 2
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: CF405M. Ex: 408nm, Em: 452nm
- Isotype: IgG1
Overview
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Product name
CF405M Anti-Integrin alpha 2 antibody [TEA1/41]
See all Integrin alpha 2 primary antibodies -
Description
CF405M Mouse monoclonal [TEA1/41] to Integrin alpha 2 -
Host species
Mouse -
Conjugation
CF405M. Ex: 408nm, Em: 452nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Human platelets (peripheral blood).
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General notes
CF405M (Abs/Em Max: 408/450 nm) US patent application no. 12/607,915. CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
TEA1/41 -
Isotype
IgG1 -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab115797 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 5µl for 106 cells.
ab126026 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| Notes |
|---|
|
Flow Cyt
Use 5µl for 106 cells. ab126026 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Function
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. -
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3673 Human
- Omim: 192974 Human
- SwissProt: P17301 Human
- Unigene: 482077 Human
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Alternative names
- BR antibody
- CD 49b antibody
- CD49 antigen like family member B antibody
see all
Images
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Flow Cytometry - CF405M Anti-Integrin alpha 2 antibody [TEA1/41] (ab115797)
ab115797 at 5µl/106 cells staining Integrin alpha 2 in Human platelets by Flow Cytometry (shown in red). Isotype control (blue).
Datasheets and documents
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Datasheet download
References (0)
ab115797 has not yet been referenced specifically in any publications.
