Key features and details
- Rabbit polyclonal to CFP10
- Suitable for: WB
- Reacts with: Species independent
- Isotype: IgG
Product nameAnti-CFP10 antibody
DescriptionRabbit polyclonal to CFP10
Specificityab45074 recognises native and E coli expressed recombinant CFP10.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Species independent
Full length protein (Mycobacterium tuberculosis)
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesPurity: > 95% (by SDS-PAGE)
Our Abpromise guarantee covers the use of ab45074 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application note: Reducing conditions.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceCFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.
- 10 kDa culture filtrate antigen cfp10 antibody
- Culture filtrate protein 10 antibody
- ESAT 6 like protein esxB antibody
ab45074 has been referenced in 4 publications.
- Lai LY et al. Role of the Mycobacterium marinum ESX-1 Secretion System in Sliding Motility and Biofilm Formation. Front Microbiol 9:1160 (2018). PubMed: 29899738
- Lou Y et al. EspC forms a filamentous structure in the cell envelope of Mycobacterium tuberculosis and impacts ESX-1 secretion. Mol Microbiol 103:26-38 (2017). PubMed: 27859904
- Sharma G et al. The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding. Nucleic Acids Res 43:3922-37 (2015). WB ; Human . PubMed: 25824946
- Ramsdell TL et al. Linked domain architectures allow for specialization of function in the FtsK/SpoIIIE ATPases of ESX secretion systems. J Mol Biol 427:1119-32 (2015). PubMed: 24979678