Key features and details
- Competitive NMDA antagonist
- CAS Number: 127910-32-1
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameCGP 39551, competitive NMDA antagonist
DescriptionCompetitive NMDA antagonist
Competitive NMDA receptor antagonist (Ki = 310 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.
Also available in simple stock solutions (ab146683) - add 1 ml of water to get an exact, ready-to-use concentration.
Chemical name(E)-4-(Ethoxycarbonyl)-4-amino-2-methylbut-2-enylphosphonic acid
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120128 has been referenced in 1 publication.
- Grauert A et al. Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells. J Physiol 592:67-86 (2014). PubMed: 24081159