CGP 7930, Positive allosteric modulator of GABAB receptors (ab120492)

Overview

  • Product name

    CGP 7930, Positive allosteric modulator of GABAB receptors
  • Description

    Positive GABAB receptor allosteric modulator
  • Biological description

    Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).
  • Purity

    > 98%
  • CAS Number

    57717-80-3
  • Chemical structure

    Chemical Structure

Properties

Associated products

References

This product has been referenced in:

  • Adams CL & Lawrence AJ CGP7930: a positive allosteric modulator of the GABAB receptor. CNS Drug Rev 13:308-16 (2007). Read more (PubMed: 17894647) »
  • Chen Y  et al. GABA(B) receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area. Br J Pharmacol 144:926-32 (2005). Read more (PubMed: 15711597) »
  • Carai MA  et al. In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor. Eur J Pharmacol 504:213-6 (2004). Read more (PubMed: 15541424) »

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