Anti-CGRP antibody (ab195387)
Key features and details
- Sheep polyclonal to CGRP
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Overview
-
Product name
Anti-CGRP antibody
See all CGRP primary antibodies -
Description
Sheep polyclonal to CGRP -
Host species
Sheep -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide corresponding to Rat CGRP. (alpha).
Database link: P01256 -
Positive control
- Rat thoracolumbar spinal cord tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Ammonium Sulphate Precipitation -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab195387 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/1000.
Perfusion fixation is recommended if possible. |
| Notes |
|---|
|
IHC-P
1/1000. Perfusion fixation is recommended if possible. |
Target
-
Relevance
CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. -
Cellular localization
Endoplasmic reticulum and Secreted -
Database links
- Entrez Gene: 171519 Rat
- Entrez Gene: 24241 Rat
- SwissProt: P01256 Rat
- SwissProt: P01257 Rat
-
Alternative names
- Calcitonin/calcitonin related polypeptide alpha antibody
- Alpha type CGRP antibody
- Beta type CGRP antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CGRP antibody (ab195387)
Immunohistochemical analysis of paraffin-embedded Rat thoracolumbar spinal cord tissue labeling CGRP with ab195387 at 1/1000 dilution. Negative images of fluorescence detection procedure (Alexa488 conjugated secondary antibody).
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab195387 has not yet been referenced specifically in any publications.