Product nameAnti-CGRP antibody
See all CGRP primary antibodies
DescriptionSheep polyclonal to CGRP
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Rat, Rabbit, Human
Synthetic peptide corresponding to Rat CGRP. (alpha).
Database link: P01256
- Rat thoracolumbar spinal cord tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityAmmonium Sulphate Precipitation
Our Abpromise guarantee covers the use of ab195387 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Perfusion fixation is recommended if possible.
RelevanceCGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.
Cellular localizationEndoplasmic reticulum and Secreted
- Calcitonin/calcitonin related polypeptide alpha antibody
- Alpha type CGRP antibody
- Beta type CGRP antibody
ab195387 has not yet been referenced specifically in any publications.