Overview

  • Product name

    Chaetoglobosin A, Antibiotic agent
  • Description

    Antibiotic agent. Phytotoxin.
  • Biological description

    Antibiotic agent. Phytotoxin. Cytochalasin analog (ab143481, ab143482, ab143483, ab143484, ab141788). Targets filamentous actin and induces apoptosis. Shows cytotoxic effects against cancer cell lines. Shows antibacterial and nematicidal effects. Induces tissue necrosis in vivo.
  • Purity

    > 98%
  • CAS Number

    50335-03-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Knudsen PB  et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28:1289-98 (2014). Read more (PubMed: 24280868) »
  • Hu Y  et al. Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. J Agric Food Chem 61:41-6 (2013). Read more (PubMed: 23214998) »
  • Ohtsubo K  et al. Acute toxic effects of chaetoglobosin A, a new cytochalasan compound produced by Chaetomium globosum, on mice and rats. Jpn J Exp Med 48:105-10 (1978). Read more (PubMed: 713122) »

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