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    chemokine-receptor-d6-antibody-ab125224.pdf

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Immunology Innate Immunity Chemokines Beta Chemokine Rec. (CCR)
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Anti-Chemokine Receptor D6 antibody (ab125224)

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Western blot - Anti-Chemokine Receptor D6 antibody (ab125224)

    Key features and details

    • Rabbit polyclonal to Chemokine Receptor D6
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

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    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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    Overview

    • Product name

      Anti-Chemokine Receptor D6 antibody
      See all Chemokine Receptor D6 primary antibodies
    • Description

      Rabbit polyclonal to Chemokine Receptor D6
    • Host species

      Rabbit
    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse
    • Immunogen

      Synthetic peptide corresponding to the C-terminal sequence of Human Chemokine Receptor D6. Sequence differs from the related rat and mouse sequences by one amino acid.

    • Positive control

      • HeLa whole cell lysate, SW620 whole cell lysate, A549 whole cell lysate, MM231 whole cell lysate, SMMC whole cell lysate.
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
      Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Immunology
      • Innate Immunity
      • Chemokines
      • Beta Chemokine Rec. (CCR)

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Positive Controls

      • HeLa whole cell lysate (ab29545)
      • A549 whole cell lysate (ab7910)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab125224 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.
    Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

    Target

    • Function

      Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.
    • Tissue specificity

      Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession O00590 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 1238 Human
      • Entrez Gene: 59289 Mouse
      • Omim: 602648 Human
      • SwissProt: O00590 Human
      • SwissProt: O08707 Mouse
      • Unigene: 146346 Human
      • Unigene: 258105 Mouse
      • Alternative names

        • C C chemokine receptor D6 antibody
        • C-C chemokine receptor D6 antibody
        • CC chemokine binding receptor JAB61 antibody
        • CC chemokine receptor D6 antibody
        • CCBP 2 antibody
        • CCBP2 antibody
        • CCBP2_HUMAN antibody
        • CCR 10 antibody
        • CCR 9 antibody
        • CCR10 antibody
        • CCR9 antibody
        • Chemokine (C C motif) receptor 9 antibody
        • Chemokine (C C) receptor 9 antibody
        • Chemokine binding protein 2 antibody
        • Chemokine binding protein D6 antibody
        • Chemokine C C motif receptor 9 antibody
        • Chemokine C C receptor 9 antibody
        • Chemokine CC motif receptor 9 antibody
        • Chemokine CC receptor 9 antibody
        • Chemokine receptor 9 antibody
        • Chemokine receptor CCR 10 antibody
        • Chemokine receptor CCR 9 antibody
        • Chemokine receptor CCR-10 antibody
        • Chemokine receptor CCR-9 antibody
        • Chemokine receptor CCR10 antibody
        • Chemokine receptor CCR9 antibody
        • Chemokine receptor D6 antibody
        • Chemokine-binding protein 2 antibody
        • Chemokine-binding protein D6 antibody
        • CMKBR 9 antibody
        • CMKBR9 antibody
        • D6 antibody
        • hD6 antibody
        • MGC126678 antibody
        • MGC138250 antibody
        see all

      Images

      • Western blot - Anti-Chemokine Receptor D6 antibody (ab125224)
        Western blot - Anti-Chemokine Receptor D6 antibody (ab125224)
        All lanes : Anti-Chemokine Receptor D6 antibody (ab125224) at 1 µg/ml

        Lane 1 : HeLa whole cell lysate
        Lane 2 : SW620 whole cell lysate
        Lane 3 : A549 whole cell lysate
        Lane 4 : MM231 whole cell lysate
        Lane 5 : SMMC whole cell lysate

        Predicted band size: 43 kDa

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (0)

      Publishing research using ab125224? Please let us know so that we can cite the reference in this datasheet.

      ab125224 has not yet been referenced specifically in any publications.

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