Overview

  • Product name
    Anti-Chemokine Receptor D6 antibody
    See all Chemokine Receptor D6 primary antibodies
  • Description
    Rabbit polyclonal to Chemokine Receptor D6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human Chemokine Receptor D6 aa 1-100 (N terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.

  • Positive control
    • Human breast carcinoma and hepatocarcinoma tissue and mouse liver tissue lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab38567 was purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab38567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 43 kDa (predicted molecular weight: 40 kDa).

Target

  • Function
    Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.
  • Tissue specificity
    Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C chemokine receptor D6 antibody
    • C-C chemokine receptor D6 antibody
    • CC chemokine binding receptor JAB61 antibody
    • CC chemokine receptor D6 antibody
    • CCBP 2 antibody
    • CCBP2 antibody
    • CCBP2_HUMAN antibody
    • CCR 10 antibody
    • CCR 9 antibody
    • CCR10 antibody
    • CCR9 antibody
    • Chemokine (C C motif) receptor 9 antibody
    • Chemokine (C C) receptor 9 antibody
    • Chemokine binding protein 2 antibody
    • Chemokine binding protein D6 antibody
    • Chemokine C C motif receptor 9 antibody
    • Chemokine C C receptor 9 antibody
    • Chemokine CC motif receptor 9 antibody
    • Chemokine CC receptor 9 antibody
    • Chemokine receptor 9 antibody
    • Chemokine receptor CCR 10 antibody
    • Chemokine receptor CCR 9 antibody
    • Chemokine receptor CCR-10 antibody
    • Chemokine receptor CCR-9 antibody
    • Chemokine receptor CCR10 antibody
    • Chemokine receptor CCR9 antibody
    • Chemokine receptor D6 antibody
    • Chemokine-binding protein 2 antibody
    • Chemokine-binding protein D6 antibody
    • CMKBR 9 antibody
    • CMKBR9 antibody
    • D6 antibody
    • hD6 antibody
    • MGC126678 antibody
    • MGC138250 antibody
    see all

Images

  • Anti-Chemokine Receptor D6 antibody (ab38567) at 1/500 dilution + Mouse liver tissue lysate

    Predicted band size: 40 kDa
    Observed band size: 43 kDa (why is the actual band size different from the predicted?)
    Additional bands at: 27 kDa, 80 kDa. We are unsure as to the identity of these extra bands.

  • Formalin fixed and paraffin embedded human breast carcinoma tissue stained with ab38567, followed by AEC staining.

References

This product has been referenced in:
  • Xu Z  et al. C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. J Am Heart Assoc 5:N/A (2016). Read more (PubMed: 27146447) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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