Chicago Sky Blue 6B, counterstain for background autofluorescence (ab145592)

Overview

  • Product name

    Chicago Sky Blue 6B, counterstain for background autofluorescence
  • Description

    Counterstain for background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor.
  • Biological description

    Counterstain for background autofluorescence. Allosteric MIF inhibitor. VGLUT inhibitor. Inhibits MIF-directed proinflammatory activity. Potently inhibits L-glutamate uptake into synaptic vesicles. Shows central effects in vivo. Centrally active.
  • Purity

    > 80%
  • CAS Number

    2610-05-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (6E)-4-Amino-6-[[4-[4-[(2Z)-2-(8-amino-1-oxo-5,7-disulfonatonaphthalen-2-ylidene)hydrazinyl]-3-methoxyphenyl]-2-methoxyphenyl]hydrazinylidene]-5-oxonaphthalene-1,3-disulfonate tetrasodium salt
  • Molecular weight

    992.79
  • Molecular formula

    C34H24N6Na4O16S4
  • PubChem identifier

    5359775
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=CC(=C1)C2=CC(=C(C=C2)NN=C3C=CC4=C(C3=O)C(=C(C=C4S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)NN=C5C=CC6=C(C5=O)C(=C(C=C6S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • He Z  et al. Inhibition of vesicular glutamate transporters contributes to attenuate methamphetamine-induced conditioned place preference in rats. Behav Brain Res 267:1-5 (2014). Read more (PubMed: 24613241) »
  • Bai F  et al. A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF). J Biol Chem 287:30653-63 (2012). Read more (PubMed: 22782901) »
  • Mohammed AK & McKenzie KT Photocatalytic degradation of Chicago Sky Blue 6B and Benzopurpurin 4B using titanium dioxide thin film. J Environ Sci (China) 17:869-72 (2005). Read more (PubMed: 16313022) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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