Overview

  • Product name

    Cholesterol, water-permeable lipid
  • Description

    Water-permeable lipid and major component of all biological membranes
  • Biological description

    Water-permeable lipid and major component of all biological membranes. Distributed in body tissues, especially the brain and spinal cord. Inhibits basal channel activity in the brain. Use as emulsifying agent and liposome preparations. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    57-88-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
  • Molecular weight

    386.65
  • Molecular formula

    C27H46O
  • PubChem identifier

    5997
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in hot ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Mathai JC  et al. Structural determinants of water permeability through the lipid membrane. J Gen Physiol 131:69-76 (2008). Read more (PubMed: 18166626) »
  • Krut LH Solubility of cholesterol in vitro promoted by oxidation products of cholesterol. Atherosclerosis 43:95-104 (1982). Read more (PubMed: 7092986) »
  • Kirby C  et al. Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro. Biochem J 186:591-8 (1980). Read more (PubMed: 7378067) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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