Key features and details
- Rabbit polyclonal to CHORDC1
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-CHORDC1 antibody
See all CHORDC1 primary antibodies
DescriptionRabbit polyclonal to CHORDC1
SpecificityAt least two isoforms of CHORDC1 are known to exist; ab106594 will recognize both isoforms.
Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
Species reactivityReacts with: Mouse, Rat, Human
21 amino acid peptide from near the N terminus of Human CHORDC1 (NP_036256).
- 293 cells and cell lysate
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAffinity chromatography purified via peptide column
Our Abpromise guarantee covers the use of ab106594 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.|
|ICC||Use a concentration of 2.5 µg/ml.|
FunctionRegulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
Tissue specificityUnderexpressed in many breast and lung cancers.
Sequence similaritiesContains 2 CHORD domains.
Contains 1 CS domain.
- Information by UniProt
- CHORD containing protein 1 antibody
- Chord domain containing protein 1 antibody
- CHORD domain-containing protein 1 antibody
Lane 1 : Anti-CHORDC1 antibody (ab106594) at 1 µg/ml
Lane 2 : Anti-CHORDC1 antibody (ab106594) at 2 µg/ml
All lanes : 293 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 37 kDa
Immunofluorescence of CHORDC1 in 293 cells with ab106594 at 20 ?g/mL.
ab106594 at 2.5 µg/ml detecting CHORDC1 in 293 cells by Immunocytochemistry.
ab106594 has not yet been referenced specifically in any publications.