Anti-Choriogonadotropin subunit beta 3 antibody [INN-hCG-2] (ab11388)
Key features and details
- Mouse monoclonal [INN-hCG-2] to Choriogonadotropin subunit beta 3
- Suitable for: ELISA, IHC-P, RIA
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-Choriogonadotropin subunit beta 3 antibody [INN-hCG-2]
See all Choriogonadotropin subunit beta 3 primary antibodies -
Description
Mouse monoclonal [INN-hCG-2] to Choriogonadotropin subunit beta 3 -
Host species
Mouse -
Tested applications
Suitable for: ELISA, IHC-P, RIAmore details
Unsuitable for: Flow Cyt -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human Choriogonadotropin subunit beta 3.
Database link: P0DN86 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
INN-hCG-2 -
Myeloma
P3-NS1/1-Ag4-1 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab11388 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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RIA |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
RIA
Use at an assay dependent concentration. |
Target
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Function
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. -
Tissue specificity
High expression in the placenta throughout pregnancy. -
Sequence similarities
Belongs to the glycoprotein hormones subunit beta family. -
Developmental stage
Expressed continuously during the whole pregnancy with a peak during the first trimester. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1082 Human
- SwissProt: P0DN86 Human
- Unigene: 172944 Human
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Alternative names
- CG-beta antibody
- CGB3_HUMAN antibody
- CGB8 antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab11388 has been referenced in 1 publication.
- Woldemariam GA & Butch AW Immunoextraction-tandem mass spectrometry method for measuring intact human chorionic gonadotropin, free ß-subunit, and ß-subunit core fragment in urine. Clin Chem 60:1089-97 (2014). PubMed: 24899693