Product nameAnti-CHREBP antibody
See all CHREBP primary antibodies
DescriptionRabbit polyclonal to CHREBP
Tested applicationsSuitable for: IHC-P, WB, ICC/IF, ChIPmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide, corresponding to C terminal amino acids 800-852 of Human CHREBP
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituent: Tris citrate/phosphate
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Integration of energy
ChIP Related Products
Our Abpromise guarantee covers the use of ab92809 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ICC/IF: 1/100 - 1/500.
IHC-P: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 95 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionTranscriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
Tissue specificityExpressed in liver, heart, kidney, cerebellum and intestinal tissues.
Involvement in diseaseNote=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
- Information by UniProt
- carbohydrate response element binding protein antibody
- bHLHd14 antibody
- Carbohydrate responsive element binding protein antibody
Anti-CHREBP antibody (ab92809) (anti CHREBP) + human hepatocyte lysate at 20 µg
Predicted band size: 95 kDa
5-10 second film exposure
anti CHREBP staining CHREBP in colon epithelium (40X) by immunohistochemistry.
anti CHREBP staining CHREBP in human hepatocyte by Immunofluorescence. Overlay staining of ChREBP (rhodamine red) and DAPI nuclear staining (blue).
This product has been referenced in:
- Zhang Y et al. Berberine reverses abnormal expression of L-type pyruvate kinase by DNA demethylation and histone acetylation in the livers of the non-alcoholic fatty disease rat. Int J Clin Exp Med 8:7535-43 (2015). Read more (PubMed: 26221297) »
- Erion DM et al. The role of the carbohydrate response element-binding protein in male fructose-fed rats. Endocrinology 154:36-44 (2013). WB . Read more (PubMed: 23161873) »