Product nameAnti-CHRFAM7A antibody
See all CHRFAM7A primary antibodies
DescriptionRabbit polyclonal to CHRFAM7A
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
- Jurkat cell lysate
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab28885 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 45 - 56 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
RelevanceThe nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. CHRFAM7A is encoded by a hybrid gene consisting of a duplication of exons 5 through 10 of the CHRNA7 gene fused 3-prime to a copy of the FAM7A gene (exons A through E). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel.
Cellular localizationMembrane; Multi-pass membrane protein.
- Alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid antibody
- CHRNA7 (cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A (family with sequence similarity 7A exons A E) fusion antibody
- CHRNA7 antibody
Anti-CHRFAM7A antibody (ab28885) at 0.5 µg/ml + Jurkat cell lysate
HRP conjugated anti-Rabbit IgG (suggested dilution 1:50000 - 100000)
Developed using the ECL technique.
Predicted band size: 45 - 56 kDa
Observed band size: 40 kDa why is the actual band size different from the predicted?
ab28885 has not yet been referenced specifically in any publications.