Overview

  • Product name

  • Description

    Rabbit polyclonal to CHRNA6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, IHC-Fr, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from C terminal of human CHRNA6.

Properties

Applications

Our Abpromise guarantee covers the use of ab65168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB 1/200 - 1/1000. Predicted molecular weight: 57 kDa.

Target

  • Relevance

    Nicotinic acetylcholine receptors (nAChRs, AChRs) are protein complexes made up of protein subunits that coassemble to form an ion channel. This ion channel is gated through the binding of the neurotransmitter acetylcholine (ACh) to its ligand-binding site on the AChR. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA6 (cholinergic nicotinic receptor alpha polypeptide 6) is a neuronal acetylcholine receptor protein.
  • Cellular localization

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • AChR-alpha6 antibody
    • Acra6 antibody
    • Cholinergic receptor nicotinic alpha 6 antibody
    • Cholinergic receptor nicotinic alpha polypeptide 6 antibody
    • CHRNA 6 antibody
    • nAChR alpha 6 antibody
    • NACHRA6 antibody
    • Neuronal acetylcholine receptor subunit alpha 6 antibody
    • Nicotinic acetylcholine receptor alpha6 antibody
    see all

References

This product has been referenced in:

  • Qian J  et al. Nicotinic acetylcholine receptor (CHRN) expression and function in cultured human adult fungiform (HBO) taste cells. PLoS One 13:e0194089 (2018). Read more (PubMed: 29513745) »
  • Munguba GC  et al. Effects of glaucoma on Chrna6 expression in the retina. Curr Eye Res 38:150-7 (2013). Read more (PubMed: 23002780) »
See all 2 Publications for this product

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