Key features and details
- Mouse monoclonal [CGA414] to Chromogranin A
- Suitable for: IHC-P, IP, IHC-Fr, Flow Cyt, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Chromogranin A antibody [CGA414]
See all Chromogranin A primary antibodies
DescriptionMouse monoclonal [CGA414] to Chromogranin A
Tested applicationsSuitable for: IHC-P, IP, IHC-Fr, Flow Cyt, ICC/IF, WBmore details
Species reactivityReacts with: Human
Recombinant full length protein corresponding to Human Chromogranin A aa 19-457.
LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILS ILRHQNLLKE LQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAE LKEAVEEPSSKDVMEKREDSKE AEKSGEATDGARPQALPEPMQESKAE GNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQ AEGDSEGLSQGLVD REKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHP SL GYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMA VVPQGLFR GGKSGELEQEEERLSKEWEDSKRWSKMDQLAKELTAEKRL EGQEEEEDNRDSSMKLSFRA RAYGFRGPGPQLRRGWRPSSREDSLEAG LPLQVRGYPEEKKEEEGSANRRPEDQELESLS AIEAELEKVAHQLQAL RRG
Database link: P10645
- Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA
Concentration information loading...
PurityProtein G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab187368 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|IP||Use at an assay dependent concentration.
1-2µg/500µg protein lysate
|IHC-Fr||Use a concentration of 0.5 - 1 µg/ml.|
|Flow Cyt||Use 0.5-1µg for 106 cells.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use a concentration of 1 - 2 µg/ml.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 68-75 kDa (predicted molecular weight: 50 kDa).|
FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
modificationsSulfated on tyrosine residues and/or contains sulfated glycans.
O-glycosylated with core 1 or possibly core 8 glycans.
Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.
- Information by UniProt
FormAccording to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
- beta Granin antibody
- betagranin (N-terminal fragment of chromogranin A) antibody
- catestatin antibody
ab187368 has not yet been referenced specifically in any publications.