Overview

  • Product name

    Anti-Chromogranin A antibody [CHGA/798]
    See all Chromogranin A primary antibodies
  • Description

    Mouse monoclonal [CHGA/798] to Chromogranin A
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human Chromogranin A.
    Database link: P10645

  • Positive control

    • Human SC lung carcinoma, Human pancreas, rat pancreas, Human parathyroid and Human adrenal gland tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab220191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.25 - 0.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similarities

    Belongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications

    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localization

    Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • Database links

  • Form

    According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • Alternative names

    • beta Granin antibody
    • betagranin (N-terminal fragment of chromogranin A) antibody
    • catestatin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • chromofungin antibody
    • Chromogranin A antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • Secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • vasostatin 2 antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    • vasostatin-2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded Human adrenal gland tissue labeling Chromogranin A with ab220191 at 0.5 μg/ml dilution.

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded Human parathyroid tissue labeling Chromogranin A with ab220191 at 0.5 μg/ml dilution.

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat pancreas tissue labeling Chromogranin A with ab220191 at 0.5 μg/ml dilution.

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded Human pancreas tissue labeling Chromogranin A with ab220191 at 0.5 μg/ml dilution.

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded Human SC lung carcinoma tissue labeling Chromogranin A with ab220191 at 0.5 μg/ml dilution.

References

ab220191 has not yet been referenced specifically in any publications.

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