Chrysamine G, beta-amyloid inhibitor (ab219402)
Overview
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Product name
Chrysamine G, beta-amyloid inhibitor -
Description
β-amyloid inhibitor -
Alternative names
- Brasilamina Yellow G
- C.I. Direct Yellow 1
- Chrysamine
see all -
Biological description
Lipophilic, carboxylic acid analog of Congo red (ab145645), shown to bind to the β-amyloid protein in vitro. Binding to the β-amyloid protein inhibits its neurodegenerative activity. Chrysamine G inhibits β-amyloid due to its antioxidant acitvity. Crosses the blood-brain barrier and serves as a useful probe for detecting β-amyloid aggregates.
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CAS Number
6472-91-9 -
Chemical structure
Properties
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Chemical name
4,4'-Bis(3-carboxy-4-hydroxyphenylazo)biphenyl
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Molecular weight
482.44 -
Molecular formula
C26H16N4O6 -
PubChem identifier
6913223 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O)NN=C4C=CC(=O)C(=C4)C(=O)O -
Source
Synthetic
Associated products
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Related Products
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab219402 has not yet been referenced specifically in any publications.
