Anti-Chymotrypsin antibody [4E1] (ab35694)
- Datasheet
- References (5)
- Protocols
Overview
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Product name
Anti-Chymotrypsin antibody [4E1]
See all Chymotrypsin primary antibodies -
Description
Mouse monoclonal [4E1] to Chymotrypsin -
Host species
Mouse -
Tested applications
Suitable for: IHC-P, ICC/IF, IHC-Fr, ELISA, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Full length native pancreatic protein (purified) (Human)
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.2 -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
4E1 -
Isotype
IgG3 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab35694 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P | Use at an assay dependent concentration. | |
ICC/IF | Use at an assay dependent concentration. | |
IHC-Fr | 1/100 - 1/800. | |
ELISA | 1/20000. | |
WB | 1/400 - 1/4000. Predicted molecular weight: 29 kDa. |
Target
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Function
Has chymotrypsin-type protease activity and hypocalcemic activity. -
Tissue specificity
Pancreas. -
Involvement in disease
Variations in CTRC influence susceptibility to chronic pancreatitis [MIM:167800]. Chronic pancreatitis is a persistent inflammatory disorder characterized by permanent destruction of the pancreatic parenchyma. -
Sequence similarities
Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain. - Information by UniProt
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Database links
- Entrez Gene: 11330 Human
- Entrez Gene: 76701 Mouse
- Entrez Gene: 362653 Rat
- Omim: 601405 Human
- SwissProt: Q99895 Human
- SwissProt: Q3SYP2 Mouse
- SwissProt: P55091 Rat
- Unigene: 631869 Human
see all -
Alternative names
- Caldecrin antibody
- Chymotrypsin C antibody
- Chymotrypsin-C antibody
see all
Protocols
Datasheets and documents
References
This product has been referenced in:
- Song Y et al. Label-Free Quantitative Proteomics Unravels Carboxypeptidases as the Novel Biomarker in Pancreatic Ductal Adenocarcinoma. Transl Oncol 11:691-699 (2018). WB ; Human . Read more (PubMed: 29631213) »
- Hong X et al. Challenges in detecting pre-malignant pancreatic lesions during acute pancreatitis using a serum microRNA assay: a study based on KrasG12D transgenic mice. Oncotarget 7:22700-10 (2016). Read more (PubMed: 27009811) »