Overview

  • Product name

    Anti-cIAP1 antibody - N-terminal
    See all cIAP1 primary antibodies
  • Description

    Rabbit polyclonal to cIAP1 - N-terminal
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous level of total cIAP1 protein.
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human cIAP1 (N terminal).
    Database link: Q13490

  • Positive control

    • Jurkat, HeLa and HT29 cell extract. Rat kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab196592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 70 kDa.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
  • Tissue specificity

    Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the IAP family.
    Contains 3 BIR repeats.
    Contains 1 CARD domain.
    Contains 1 RING-type zinc finger.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • API 1 antibody
    • API1 antibody
    • Apoptosis inhibitor 1 antibody
    • Baculoviral IAP repeat containing 2 antibody
    • Baculoviral IAP repeat containing protein 2 antibody
    • Baculoviral IAP repeat-containing protein 2 antibody
    • BIRC 2 antibody
    • BIRC2 antibody
    • BIRC2_HUMAN antibody
    • C IAP1 antibody
    • C-IAP1 antibody
    • Cellular inhibitor of apoptosis 1 antibody
    • cellular inhibitor of apoptosis protein 1 antibody
    • cIAP 1 antibody
    • cIAP1 antibody
    • HIAP 2 antibody
    • HIAP-2 antibody
    • HIAP2 antibody
    • IAP 2 antibody
    • IAP homolog B antibody
    • IAP-2 antibody
    • IAP2 antibody
    • Inhibitor of apoptosis protein 2 antibody
    • MIHB antibody
    • NFR2 TRAF signalling complex protein antibody
    • RING finger protein 48 antibody
    • RNF 48 antibody
    • RNF48 antibody
    • TNFR2 TRAF signaling complex protein 2 antibody
    • TNFR2-TRAF-signaling complex protein 2 antibody
    see all

Images

  • All lanes : Anti-cIAP1 antibody - N-terminal (ab196592) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : HeLa cell extract
    Lane 3 : HT29 cell extract

    Predicted band size: 70 kDa

  • Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue labeling cIAP1 using ab196592 at a 1/200 dilution.

  • Immunohistochemical analysis of paraffin-embedded rat kidney tissue labeling cIAP1 using ab196592 at a 1/200 dilution.

  • Immunofluorescence analysis of A549 cells labeling cIAP1 using ab195692 at a 1/50 dilution.

References

ab196592 has not yet been referenced specifically in any publications.

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