Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab38272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-cIAP1 antibody (ab2399)

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • API 1
    • API1
    • Apoptosis inhibitor 1
    • Baculoviral IAP repeat containing 2
    • Baculoviral IAP repeat containing protein 2
    • Baculoviral IAP repeat-containing protein 2
    • BIRC 2
    • BIRC2
    • BIRC2_HUMAN
    • C IAP1
    • C-IAP1
    • cIAP 1
    • cIAP1
    • HIAP 2
    • HIAP-2
    • HIAP2
    • IAP 2
    • IAP homolog B
    • IAP-2
    • IAP2
    • Inhibitor of apoptosis protein 2
    • MIHB
    • NFR2 TRAF signalling complex protein
    • RING finger protein 48
    • RNF 48
    • RNF48
    • TNFR2 TRAF signaling complex protein 2
    • TNFR2-TRAF-signaling complex protein 2
    see all
  • Function
    Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
  • Tissue specificity
    Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the IAP family.
    Contains 3 BIR repeats.
    Contains 1 CARD domain.
    Contains 1 RING-type zinc finger.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab38272 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Answer

Thank you for your email.

The peptide is from the sequence around amino acid 530 of human cIAP1. This sequence does not match with the immunogen sequence of polyclonal and monoclonal antibodies you have so this peptide ab38272 would be of no use.

If you are interested in doing blocking experiment then ab38272 would block ab2399.

I hope this information will be helpful. Should you have any question please do not hesitate to contact me.

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Answer

Thank you for contacting us.

Could you please explain what do you mean by other antibodies? The antibodies against the same peptide should be same however difference can be seen in specificity, purity etc.

The peptide ab38272 is from a sequence flanking 530 of human cIAP1. We unfortunately don't know the exact sequence so this peptide may not able to block your antibody.

Do you know the immunogen sequence of your antibody?

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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