Key features and details
- Rabbit polyclonal to CIB1/KIP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CIB1/KIP antibody
See all CIB1/KIP primary antibodies
DescriptionRabbit polyclonal to CIB1/KIP
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
- Recombinant Human CIB1/KIP protein (ab78759) can be used as a positive control in WB. This antibody gave a positive signal with recombinant CIB1/KIP protein.
This product was previously labelled as CIB1
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab43133 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).|
FunctionMay convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through binding to the integrin cytoplasmic domain. Induces cell migration and spreading mediated through integrin (possibly via focal adhesion complexes). Functions as a negative regulator of stress activated MAP kinase (MAPK) signaling pathways. May play a role in regulation of apoptosis. Interacts with and up-regulates PTK2 activity. Down regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling.
Sequence similaritiesContains 2 EF-hand domains.
Cellular localizationMembrane. Cytoplasm. Nucleus. Cell projection > filopodium. Apical cell membrane. Localizes to the perinuclear region in the presence of NBR1. Colocalizes with TAS1R2 in apical regions of taste receptor cells.
- Information by UniProt
- Calcium and integrin binding 1 (calmyrin) antibody
- Calcium and integrin binding protein 1 antibody
- Calcium and integrin-binding protein 1 antibody
Anti-CIB1/KIP antibody (ab43133) at 1 µg/ml + Recombinant Human CIB1/KIP protein (ab40628) at 0.1 µg
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) (ab65484) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 22 kDa
Observed band size: 22 kDa
Exposure time: 30 seconds
ab43133 has not yet been referenced specifically in any publications.