Ciclopirox ethanolamine (Ciclopirox olamine), Na+ K+ ATPase substrate (ab143286)

Overview

  • Product name

    Ciclopirox ethanolamine (Ciclopirox olamine), Na+ K+ ATPase substrate
  • Description

    Broad spectrum antifungal agent. Na+ K+ ATPase substrate.
  • Alternative names

    • Ciclopirox olamine
  • Biological description

    Broad spectrum antifungal agent. Na+ K+ ATPase substrate. Ciclopirox (ab143203) analog. Iron chelator. Disrupts DNA repair, cell division signals and mitotic spindles. Inhibits the translation initiation factor eIF5A. Inhibits mTOR. Shows antitumor effects. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    41621-49-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mémin E  et al. Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation. Cancer Res 74:552-62 (2014). Read more (PubMed: 24220243) »
  • Schmeel LC  et al. Targeting the Wnt/beta-catenin pathway in multiple myeloma. Anticancer Res 33:4719-26 (2013). Read more (PubMed: 24222106) »
  • Sen S  et al. Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity. Exp Hematol 41:799-807.e4 (2013). Read more (PubMed: 23660068) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143286.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up