Cinchophen, Antimicrobial agent (ab145792)

Overview

  • Product name

    Cinchophen, Antimicrobial agent
  • Description

    Non-steroidal analgesic, antipyretic and anti-inflammatory drug. Powerful antimicrobial agent
  • Alternative names

    • 2-Phenyl-4-quinolinecarboxylic acid
    • 2-Phenylcinchoninic acid
    • 2-Phenylquinoline-4-carboxylic acid
    • Atophan
    • Phenaquin
    • Quinophan
    see all
  • Biological description

    Non-steroidal analgesic, antipyretic and anti-inflammatory drug used in animals. Powerful antimicrobial agent. No longer used in humans as can cause serious liver damage.

  • Purity

    > 99%
  • CAS Number

    132-60-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Phenyl-4-quinolinecarboxylic acid
  • Molecular weight

    249.26
  • Molecular formula

    C16H11NO2
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Strigácová J  et al. Some biological properties of new quinoline-4-carboxylic acid and quinoline-4-carboxamide derivatives. Folia Microbiol (Praha) 45:305-9 (2000). Read more (PubMed: 11347250) »
  • Jingu H & Miura M Ulcerogenic cinchophen induces c-Fos expression in CRH-secreting cells in the PVH of rat brain. Neuroreport 7:2649-53 (1996). Read more (PubMed: 8981440) »
  • Takayama K  et al. Neuronal expression of Fos protein in the paraventricular nucleus of the hypothalamus after i.p. injection of ulcergenic cinchophen. Neurosci Lett 172:55-8 (1994). Read more (PubMed: 7916144) »
  • Cutrín Prieto C  et al. [Toxic hepatitis from cinchophen: report of 3 cases]. Med Clin (Barc) 97:104-6 (1991). Read more (PubMed: 1679861) »
  • Hänninen O & Hartiala K Inhibition of transaminases by cinchophen and its derivatives. Biochem Pharmacol 14:1073-6 (1965). Read more (PubMed: 4379145) »

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