Overview

  • Product name
    Cinepazide maleate, calcium channel blocker
  • Description
    Calcium channel blocker. Vasodilator.
  • Biological description
    Calcium channel blocker. Shows positive inotropic and chronotropic effects. Shows vasodilatory and anti-ischemic effects in vivo. Orally active.

Properties

  • Chemical name
    (E)-1-[4-(2-Oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one maleate
  • Molecular weight
    533.57
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C22H31N3O5.C4H4O4
  • CAS Number
    26328-04-1
  • PubChem identifier
    5282458
  • Storage instructions
    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCN(CC2)CC(=O)N3CCCC3.C(=CC(=O)O)C(=O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Yamamoto M  et al. Cerebral vasodilators potentiate the anti-anoxic activity of indeloxazine hydrochloride, a new cerebral activator. Neuropharmacology 28:313-7 (1989). Read more (PubMed: 2725854) »
  • Miwa S  et al. The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia. Jpn J Pharmacol 41:109-15 (1986). Read more (PubMed: 2426499) »
  • Marteau P  et al. Effect of vasodilators on hepatic microcirculation: a study of the inhibition of norepinephrine-induced vasoconstriction in the isolated perfused rat liver. Hepatology 8:228-31 (0). Read more (PubMed: 3356403) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143352.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up