Overview

  • Product name

    Cinnarizine, Calcium channel antagonist
  • Description

    Calcium channel antagonist
  • Biological description

    Selective antagonist of T-type voltage-operated calcium ion channels. Antihistaminergic, antiserotoninergic and antidopaminergic effects in vitro.
  • Purity

    > 98%
  • CAS Number

    298-57-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
  • Molecular weight

    368.51
  • Molecular formula

    C26H28N2
  • PubChem identifier

    1547484
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Nagai H  et al. Effect of cinnarizine on IgE antibody-mediated experimental allergic reactions in guinea pigs. Allergy 42:135-40 (1987). Read more (PubMed: 2438961) »
  • Nghiem C  et al. Inhibition by cinnarizine of the responses of smooth muscle from spontaneously hypertensive and normotensive rats. Can J Physiol Pharmacol 61:1523-5 (1983). Read more (PubMed: 6671165) »

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