- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-CINP antibody
See all CINP primary antibodies -
DescriptionRabbit polyclonal to CINP
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Host speciesRabbit
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Tested applicationsSuitable for: WB, Flow Cytmore details
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Species reactivityReacts with: Human
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Immunogen
Synthetic peptide within Human CINP (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
Database link: Q9BW66 -
Positive control
- CEM cells and lysates.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
PurityImmunogen affinity purified
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Purification notesab176181 is purified through a protein A column, followed by peptide affinity purification.
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Related Products
Applications
Our Abpromise guarantee covers the use of ab176181 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 24 kDa. | |
| Flow Cyt | 1/10 - 1/50. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
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Target
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FunctionInteracts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
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Sequence similaritiesBelongs to the CINP family.
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Post-translational
modificationsPhosphorylated by CDC7 but not by CDK2. -
Cellular localizationNucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
- Information by UniProt
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Database links
- Entrez Gene: 51550 Human
- Omim: 613362 Human
- SwissProt: Q9BW66 Human
- Unigene: 129634 Human
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Alternative names
- CDK2-interacting protein antibody
- CINP antibody
- CINP protein antibody
see all
Images
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Western blot - Anti-CINP antibody (ab176181)Anti-CINP antibody (ab176181) at 1/1000 dilution + CEM cell lysate at 35 µg
Predicted band size: 24 kDa -
Flow Cytometry - Anti-CINP antibody (ab176181)Flow cytometric analysis of CEM cells labeling CINP with ab176181 at 1/10 dilution (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-Rabbit secondary antibodies were used for the analysis.
References
ab176181 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"