Key features and details
- Rabbit polyclonal to CIP75
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-CIP75 antibody
See all CIP75 primary antibodies
DescriptionRabbit polyclonal to CIP75
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human CIP75 (N terminal).
Database link: Q9NRR5
- 3T3 cell lysate, Mouse kidney tissue.
Previously labelled as UBQLN4.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 64 kDa.|
Tissue specificityHighly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.
Sequence similaritiesContains 1 UBA domain.
Contains 1 ubiquitin-like domain.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationNucleus. Cytoplasm. Endoplasmic reticulum. May associate with the endoplasmic reticulum.
- Information by UniProt
- 28S ribosomal protein S7 antibody
- A1U antibody
- A1Up antibody
ab106443 has been referenced in 3 publications.
- Sentürk M et al. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nat Cell Biol 21:384-396 (2019). PubMed: 30804504
- Itakura E et al. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Mol Cell 63:21-33 (2016). WB ; Human . PubMed: 27345149
- Coffey RT et al. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem 291:5221-33 (2016). PubMed: 26740621