Overview

  • Product name
    Cisplatin, antineoplastic agent
  • Description
    Potent, broad spectrum antineoplastic agent
  • Biological description
    Potent, broad spectrum antineoplastic agent. Cytotoxic, crosslinks DNA to impair replication and transcription. Arrests cell cycle in G2/M phase. Antitumor, cross-linking and radiation sensitizing agent. Active in vivo and in vitro.
  • CAS Number
    15663-27-1
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • van Gijssel HE  et al. Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin. Mutagenesis 22:49-54 (2007). Read more (PubMed: 17158520) »
  • Mueller S  et al. Cell-cycle progression and response of germ cell tumors to cisplatin in vitro. Int J Oncol 29:471-9 (2006). Read more (PubMed: 16820891) »
  • Sugimoto C  et al. Apoptosis-promoting gene (bax) transfer potentiates sensitivity of squamous cell carcinoma to cisplatin in vitro and in vivo. Int J Cancer 82:860-7 (1999). Read more (PubMed: 10446454) »
See 1 Publication for this product

Customer reviews and Q&As

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Cisplatin

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It is difficult to dilute.

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Submitted Feb 27 2018

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