Overview

  • Product name

  • Description

    Rabbit polyclonal to CKMT2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Cow, Dog, Pig
  • Immunogen

    Recombinant fragment within Human CKMT2 (internal sequence). The exact sequence is proprietary.
    Database link: P17540

  • Positive control

    • IHC-P: BT483 xenograft tissue; Mouse duodenum tissue. WB: HEK-293T whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab227440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
  • Tissue specificity

    Sarcomere-specific. Found only in heart and skeletal muscles.
  • Sequence similarities

    Belongs to the ATP:guanido phosphotransferase family.
    Contains 1 phosphagen kinase C-terminal domain.
    Contains 1 phosphagen kinase N-terminal domain.
  • Cellular localization

    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CKMT 2 antibody
    • Basic-type mitochondrial creatine kinase antibody
    • CKMT2 antibody
    • CPK antibody
    • Creatine kinase mitochondrial 2 antibody
    • Creatine kinase mitochondrial 2 (sarcomeric) antibody
    • Creatine kinase S-type antibody
    • creatine kinase S-type, mitochondrial antibody
    • Creatine kinase, sarcomeric mitochondrial antibody
    • KCRS_HUMAN antibody
    • Mib CK antibody
    • Mib-CK antibody
    • mitochondrial antibody
    • OTTHUMP00000147542 antibody
    • S-MtCK antibody
    • Sarcomeric mitochondrial creatine kinase antibody
    • SMTCK antibody
    see all

Images

  • Paraffin-embedded mouse duodenum tissue stained for CKMT2 using ab227440 at 1/500 dilution in immunohistochemical analysis.

  • Anti-CKMT2 antibody (ab227440) at 1/1000 dilution + HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 30 µg

    Predicted band size: 48 kDa



    10% SDS-PAGE gel.

  • Paraffin-embedded BT483 xenograft tissue stained for CKMT2 using ab227440 at 1/500 dilution in immunohistochemical analysis.

References

ab227440 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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