Overview

  • Product name

    CL-82198, Matrix metalloprotinase -13 (MMP-13) inhibitor
  • Description

    Selective matrix metalloprotinase -13 (MMP-13) inhibitor
  • Biological description

    Selective MMP-13 inhibitor (IC50 = 3.2 μM). Displays no activity against MMP-1, MMP-9 or TACE. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    307002-71-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Wohlauer M  et al. Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13. Crit Care Med 40:2647-53 (2012). Read more (PubMed: 22732292) »
  • Rath T  et al. Matrix metalloproteinase-13 is regulated by toll-like receptor-9 in colorectal cancer cells and mediates cellular migration. Oncol Lett 2:483-488 (2011). Read more (PubMed: 22866107) »
  • Hernández Ríos M  et al. Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade. J Clin Periodontol 36:1011-7 (2009). Read more (PubMed: 19929954) »
  • Wu J  et al. Identification of potent and selective MMP-13 inhibitors. Bioorg Med Chem Lett 15:4105-9 (2005). Read more (PubMed: 16005220) »
See 1 Publication for this product

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