Anti-Claudin 10 antibody (ab24792)
Key features and details
- Rabbit polyclonal to Claudin 10
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Claudin 10 antibody
See all Claudin 10 primary antibodies -
Description
Rabbit polyclonal to Claudin 10 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide within Human Claudin 10 aa 200 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P78369 -
General notes
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
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| Notes |
|---|
|
IHC-P
1/50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
Target
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Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
Sequence similarities
Belongs to the claudin family. -
Cellular localization
Cell junction > tight junction. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9071 Human
- Entrez Gene: 58187 Mouse
- SwissProt: P78369 Human
- SwissProt: Q5W075 Human
- SwissProt: Q6IBF9 Human
- SwissProt: Q96N78 Human
- SwissProt: Q8VC62 Mouse
- SwissProt: Q9Z0S6 Mouse
see all -
Alternative names
- Claudin-10 antibody
- Claudin10 antibody
- CLD10_HUMAN antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab24792 has been referenced in 5 publications.
- Zhang X et al. CLDN10 promotes a malignant phenotype of osteosarcoma cells via JAK1/Stat1 signaling. J Cell Commun Signal N/A:N/A (2019). PubMed: 30796717
- Chae MC et al. Prognostic significance of claudin 4 in completely resected adenocarcinoma of the lung. Korean J Thorac Cardiovasc Surg 47:262-8 (2014). IHC . PubMed: 25207224
- Kirk A et al. Differential expression of claudin tight junction proteins in the human cortical nephron. Nephrol Dial Transplant 25:2107-19 (2010). IHC-Fr ; Human . PubMed: 20124215
- Dubé E et al. Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men. Biol Reprod 78:342-51 (2008). PubMed: 17928628
- Hermo L et al. Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility. J Androl 28:784-97 (2007). PubMed: 17522420