Anti-Claudin 10 antibody (ab24792)
Key features and details
- Rabbit polyclonal to Claudin 10
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Claudin 10 antibody
See all Claudin 10 primary antibodies -
Description
Rabbit polyclonal to Claudin 10 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human Claudin 10 aa 200 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P78369 -
General notes
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
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Notes |
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IHC-P
1/50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
Target
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Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
Sequence similarities
Belongs to the claudin family. -
Cellular localization
Cell junction > tight junction. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9071 Human
- Entrez Gene: 58187 Mouse
- SwissProt: P78369 Human
- SwissProt: Q5W075 Human
- SwissProt: Q6IBF9 Human
- SwissProt: Q96N78 Human
- SwissProt: Q8VC62 Mouse
- SwissProt: Q9Z0S6 Mouse
see all -
Alternative names
- Claudin-10 antibody
- Claudin10 antibody
- CLD10_HUMAN antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab24792 has been referenced in 5 publications.
- Zhang X et al. CLDN10 promotes a malignant phenotype of osteosarcoma cells via JAK1/Stat1 signaling. J Cell Commun Signal N/A:N/A (2019). PubMed: 30796717
- Chae MC et al. Prognostic significance of claudin 4 in completely resected adenocarcinoma of the lung. Korean J Thorac Cardiovasc Surg 47:262-8 (2014). IHC . PubMed: 25207224
- Kirk A et al. Differential expression of claudin tight junction proteins in the human cortical nephron. Nephrol Dial Transplant 25:2107-19 (2010). IHC-Fr ; Human . PubMed: 20124215
- Dubé E et al. Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men. Biol Reprod 78:342-51 (2008). PubMed: 17928628
- Hermo L et al. Structural alterations of epididymal epithelial cells in cathepsin A-deficient mice affect the blood-epididymal barrier and lead to altered sperm motility. J Androl 28:784-97 (2007). PubMed: 17522420